Database Authors
Ron Caspi1, Carol A Fulcher1, Anamika Kothari1, Markus Krummenacker1, Amanda Mackie2, Lisa Moore1, Suzanne Paley1, Pallavi Subhraveti1, Austin Swart1, Peter D Karp1
1SRI International, 2Macquarie University
See all credits, including past contributors.
Summary MetaCyc is a curated multi-organism database of experimentally elucidated metabolic pathways from all domains of life.

MetaCyc contains pathways involved in both primary and secondary metabolism, as well as associated metabolites, reactions, enzymes, and genes. The goal of MetaCyc is to catalog the universe of metabolism by storing a representative sample of each experimentally elucidated pathway.

See the MetaCyc home page for more information.

Database Contents
Genes16,286
Pathways3,647
Enzymatic Reactions20,039
Transport Reactions1,036
Polypeptides18,103
Protein Complexes5,044
Enzymes14,473
Transporters709
Compounds20,316
tRNAs8
Growth Media19
Protein Features35,998
GO Terms85,374
Database Version29.1 [History of Updates]
Image of mugs with the MetaCyc logo, featuring the caffeine biosynthesis pathway
The MetaCyc mug, featuring the caffeine biosynthesis pathway. This mug and others are available for purchase at the BioCyc mug shop.
Copyright © SRI International 1999-2024, Marine Biological Laboratory 1998-2001, DoubleTwist Inc 1998-1999. All Rights Reserved.

Report Errors or Provide Feedback
Please cite the following article in publications resulting from the use of MetaCyc: Caspi et al, Nucleic Acids Research 46(D1):D633-D639 2018
Page generated by Pathway Tools version 29.0 (software by SRI International) on Fri Oct 10, 2025, BIOCYC17.